ABSTRACT
US National Security Strategy adopted in October 2022. highlights the complex security challenges in Eurasia that pose a threat to US global dominance. What does the new US national security strategy mean for the EU? Namely, until recently the concept of European strategic autonomy, which affirmed not only the military, but also the specific economic interests of the EU, was marginalized by the Ukrainian crisis. Thus, in the context of the comprehensive destabilization of Europe, the security architecture of the continent is shaped by the instruments of the American security strategy, which is not always compatible with the interests of the EU. Namely, the US National Security Strategy significantly determine the geopolitical possibilities of the European Union, which is facing the deepest crisis since the Second World War.